Description

1. TB-500 (Thymosin Beta-4)

TB-500 is a synthetic fraction of the naturally occurring protein Thymosin Beta-4, which is found in high concentrations in blood platelets and wound fluid.

• Biochemical Action: Its primary mechanism of action is its ability to upregulate actin, a vital cellular protein involved in cell structure and movement. It promotes angiogenesis (new blood vessel formation) and cell migration.

• Research Focus: Investigating accelerated wound healing, tendon and ligament repair, and the reduction of inflammation in various tissue types.

2. BPC-157 (Body Protection Compound-157)

BPC-157 is a pentadecapeptide composed of 15 amino acids. It is a partial sequence of a protective compound found in human gastric juice.

• Biochemical Action: It acts by modulating the nitric oxide (NO) pathway and triggering the expression of early growth response 1 (egr-1) genes. It has also been shown to promote the expression of VEGFR2 (vascular endothelial growth factor receptor 2).

• Research Focus: Studies focused on “cytoprotection,” specifically the healing of the gastrointestinal tract, bone-to-tendon healing, and systemic anti-inflammatory effects.

3. KPV (Lysine-Proline-Valine)

KPV is a tripeptide that constitutes the C-terminal fragment of the alpha-melanocyte-stimulating hormone ($\alpha$-MSH).

• Biochemical Action: Unlike the full $\alpha$-MSH molecule, KPV does not induce pigmentation but retains potent anti-inflammatory properties. It works by inhibiting NF-$\kappa$B (nuclear factor kappa-light-chain-enhancer of activated B cells), a major signaling pathway for pro-inflammatory cytokines.

• Research Focus: Research into inflammatory bowel disease (IBD), dermatological inflammation, and general immune response modulation.

Important: Restricted to Research Use

These substances are provided exclusively for laboratory and analytical purposes.

Safety Warning: These compounds are not intended for human use, clinical diagnosis, or medical treatment. As stated on the labels (“For Research Purpose Only“), they must only be used in controlled research environments. They are not dietary supplements or drugs. Proper laboratory protocols and safety measures must be strictly followed during handling.