Description

SS-31, also known as Elamipretide, is a mitochondria-targeted peptide originally developed by researchers at Cornell University. It binds to cardiolipin, a phospholipid in the inner mitochondrial membrane, helping stabilize mitochondrial function and reduce oxidative stress. Studies published in journals such as Circulation and Journal of the American College of Cardiology have investigated its potential in cardiovascular diseases, heart failure, and mitochondrial disorders. Clinical trials have evaluated its ability to improve cellular energy production and muscle function, although results vary depending on the condition studied. The compound remains under clinical investigation for multiple mitochondrial-related indications.